Mar 23, Arrabidaea chica (HBK) Verlot, Bignoniaceae, is a scrambling shrub native to tropical America, more particularly in the Amazon basin where it. Arrabidaea chica (Humb. & Bonpl.) Verl. Show All Show Tabs cricketvine. General Information. Symbol: ARCH5. Group: Dicot. Family: Bignoniaceae. Duration. A new flavone, 6,7,3′,4′-tetrahydroxymethoxyflavone, named carajuflavone, was isolated from the leaves of the Brazilian plant Arrabidaea chica f. cuprea.

Author: Moogutilar Akilrajas
Country: Kazakhstan
Language: English (Spanish)
Genre: Education
Published (Last): 14 October 2013
Pages: 172
PDF File Size: 15.96 Mb
ePub File Size: 11.89 Mb
ISBN: 865-5-35129-477-9
Downloads: 31245
Price: Free* [*Free Regsitration Required]
Uploader: Brakree

Top of Page Home. Then promastigote forms of L. Another report showed that the hidroalcoholic extract of A. Lima de Medeiros, K. Earlier studies of A. The role of inflammatory and immune responses in tumor development is unclear. Arq Bras Endocrinol Metab In that work, n -decanoic acid, n -dodecanoic acid, and n -hexadecanoic acid were described as the main active compounds [ 19 ].

These findings suggest that A.

Evaluation of Safety of Arrabidaea chica Verlot (Bignoniaceae), a Plant with Healing Properties.

Results and Discussion In order to evaluate if Arrabidaea chica Humb. The ethanol extract did not cause alteration on the percentage of tumor infiltrating lymphocytes subpopulations. Important ultrastructural alterations as mitochondrial swelling with loss of matrix content and the presence of vesicles inside this organelle were observed in treated parasites.

Very little is known about the chemical constitution of the leaves Barbosa et al. Therefore, based on the empirical ethnopharmacological use of Arrabidaea chhica crude extract as an antitumor agent associated with the strong cytotoxic activity in vitro Ribeiro et al. Table of Contents Alerts.

There was a significant reduce in the tumor growth in mice treated with AE and EE at 12 th day, different from control group Figure 1. Leukocyte infiltration of tumors has been described as playing either inhibitory or stimulatory roles in tumor growth Bergami-Santos et al.


Arrabidaea chica extract improves gait recovery and changes collagen content during healing of the Achilles chixa. On the 10 th day of treatment, i. Inhibitory activity of the B2 fraction obtained from the A. Consequently, the search for new and more effective antileishmanial agents remains crucial.

Evaluation of wound healing properties of Arrabidaea chica Verlot extract. The authors declare that there is no conflict of interests regarding the publication of this paper. Fatty acids and sterols probably are the main components involved in the antileishmanial activity, but further investigation will be necessary in order to evaluate the isolated compounds.

Compound concentrations were calculated from the GC peak areas, and they were arranged in order of GC elution. Linear retention indices LRI were measured by injection of a series of n -alkanes in the same column and conditions wrrabidaea described above and compared with reference data. Most likely the two extracts tested here exhibit different mechanisms arrabifaea action.

Plants Profile for Arrabidaea chica (cricketvine)

We believed that the antitumoral activity of A. During the last decade, natural antioxidants, particularly phenolics, have been under very close scrutiny as potential therapeutic agents against a wide range of ailments including cancer, inflammatory diseases and also aging.

The identification of the B2 fraction constituents was made based on the retention indexes and by comparison of mass spectra with computer search using NIST21 and NIST libraries.

Measures of mice paws showed a continuous tumor growth in all experimental groups.


Dual role of polymorphonuclear neutrophils on the growth of Ehrlich ascites tumor EAT in mice. Received 25 Jan Accepted chiica Aug J Pharmacol Sci Blood samples were collected by retro-orbital puncture for hematological evaluation before the euthanasia.

The B2 fraction from arrabodaea A. Apparently the same occurs here, suggesting that other nonspecific inflammatory mechanism might be relevant in tumor resistance.

Despite the decrease in peptidase activity the results show that B2 was less effective against those peptidases.

Potential Blenders and core components note. The direct strong cytotoxic effect of ethanol extract was already demonstrated in the in vitro experiments against Jurkat and HL60 cell lines Ribeiro et al. In Brazil, CL and VL are widespread and can be found not only in rural areas chia also in urban areas mainly due to deforestation and new settlements [ 3 ].

Evaluation of Safety of Arrabidaea chica Verlot (Bignoniaceae), a Plant with Healing Properties.

Tumor growth was evaluated by measuring the inoculated footpad thickness with a graduate micrometer Mitutoyo, modelgraduation 0. Promastigote forms of two Leishmania species, Leishmania L. The selection of the dose was based on the work of Queiroz et al. Possibly the antitumor effect demonstrated here is also related to the induction of apoptosis of tumor cells. Introduction Among individual infectious diseases leishmaniasis is in the ninth position of the global burden of diseases.

Author: admin